South America Adventure Vacations & Trips
Looking for the best South America Adventure Vacations & Trips? Choose from the finest cruises available in South America, hand-picked by our destination specialists. Operated by only the most trusted of partners, these cruises have been carefully selected for their authentic design, customer service excellence, and extraordinary itineraries.
Found 48 results
Prices are displayed in USD per person in double occupancy or charter per day
Deal
Amazing Group Deal aboard the Pure Amazon cruise
Launching Offer
Deal
Charter Offer aboard the Pure Amazon
river Cruise
Private Charter
Pure Amazon
A state-of-the-art riverboat offering personalized and luxurious adventures in the Peruvian Amazon.
Regions:
Amazon, Peru
Destinations:
Peru Amazon
Cabins
/ Charter
$5,469
USD
Per Person
4 - 8 Days
3 Itineraries
22 Guests
12 Cabins
$23,750
USD
Per Day
Days +
Flexible
22 Guests
12 Cabins
coastal Cruise
Private Charter
Aqua Mare
An exclusive Galapagos superyacht experience of next-level luxury and the most personalized service.
Regions:
Galapagos, Ecuador
Destinations:
Galapagos, Bartolomé, Santa Cruz, Española, Floreana, Isabela, Fernandina
Cabins
/ Charter
$11,480
USD
Per Person
8 - 15 Days
4 Itineraries
16 Guests
7 Cabins
$238,000
USD
Entire Vessel
8 Days +
Flexible
16 Guests
7 Cabins
Deal
Up to 30% Off on Galapagos Cruises
Flight Discounts On Galapagos Cruises
coastal Cruise
Private Charter
Galaxy Sirius
A stylish, sleek, and luxurious catamaran with balcony cabins sailing shorter Galapagos cruises.
Regions:
Galapagos, Ecuador
Destinations:
Bartolomé, Española, Floreana, Isabela, North Seymour, San Cristobal, Santa Cruz
Cabins From
$5,349
USD
Per Person
5 - 6 Days
3 Itineraries
16 Guests
9 Cabins
$17,120
USD
Per Day
Days +
Flexible
16 Guests
9 Cabins
Deal
10% Off on board the Origin, Theory & Evolve
Photo Adventure aboard the Origin, Theory & Evolve
Solo Reduced Rate on board the Origin, Theory & Evolve
coastal Cruise
Private Charter
Origin, Theory & Evolve
Incredibly high-level luxury Galapagos cruising aboard stunning, state-of-the-art sister vessels.
Regions:
Galapagos, Ecuador
Destinations:
Bartolomé, Española, Fernandina, Floreana, Galapagos, Isabela, North Seymour, San Cristobal, Santa Cruz
Cabins
/ Charter
$10,479
USD
Per Person
8 - 15 Days
4 Itineraries
20 Guests
10 Cabins
$210,000
USD
Entire Vessel
8 Days +
Flexible
20 Guests
10 Cabins
Deal
Second Passenger Gets 50% Off Aboard Delfin III Amazon Cruises
2025 Photography Adventure aboard Delfin III
Photographer-Hosted Departure aboard Delfin III Amazon Cruise
2025 River Dolphin Expedition aboard Delfin III
2025 Wellness Trip aboard Delfin III
river Cruise
Private Charter
Delfin III
Beautiful and affordable 5 star luxury in the heart of the Peruvian Rainforest.
Regions:
Amazon, Peru
Destinations:
Iquitos, Peru Amazon
Cabins
/ Charter
$3,779
USD
Per Person
4 - 5 Days
2 Itineraries
44 Guests
22 Cabins
$37,500
USD
Per Day
4 Days +
Flexible
44 Guests
22 Cabins
Deal
2025 Last Minute Savings 30% or 40% off onboard the Anakonda & Manatee Cruises
Early Monkey
river Cruise
Private Charter
Anakonda
Award-winning boutique vessel exploring Ecuador's biodiverse Oriente in luxurious style.
Regions:
Amazon, Ecuador
Destinations:
Ecuador Amazon, Coca
Cabins
/ Charter
$2,979
USD
Per Person
4 - 8 Days
3 Itineraries
36 Guests
18 Cabins
$26,135
USD
Per Day
4 Days +
Flexible
36 Guests
18 Cabins
coastal Cruise
Private Charter
Nat Geo Delfina
An elegant catamaran offering intimate, expert-led Galapagos cruises with panoramic wildlife viewing.
Regions:
Ecuador, Galapagos
Destinations:
North Seymour, Bartolomé, Isabela, Fernandina, Española, Floreana, Santa Cruz, San Cristobal
Cabins From
$14,189
USD
Per Person
8 Days
2 Itineraries
16 Guests
8 Cabins
$0
USD
Per Day
Days +
Flexible
16 Guests
8 Cabins
Deal
Early Booking Promotion aboard the Magellan Explorer
coastal Cruise
Private Charter
Magellan Explorer
A pioneering polar expedition ship providing a luxurious, stylish base for Patagonian adventures.
Regions:
Chile, Patagonia
Destinations:
Patagonia, Ushuaia, Puerto Montt
Cabins From
$5,995
USD
Per Person
9 Days
2 Itineraries
76 Guests
38 Cabins
$0
USD
Per Day
Days +
Flexible
76 Guests
38 Cabins
