South America Adventure Vacations & Trips
Looking for the best South America Adventure Vacations & Trips? Choose from the finest cruises available in South America, hand-picked by our destination specialists. Operated by only the most trusted of partners, these cruises have been carefully selected for their authentic design, customer service excellence, and extraordinary itineraries.
Found 43 results
Prices are displayed in USD per person in double occupancy
Deal
Stay 4 Nights, Pay 3 Aboard the Delfin III
river Cruise
Private Charter
Delfin III
Beautiful and affordable 5 star luxury in the heart of the Peruvian Rainforest.
Regions:
Amazon, Peru
Destinations:
Iquitos, Peru Amazon
Cabins
/ Charter
$4,179
USD
Per Person
4 - 5 Days
2 Itineraries
44 Guests
22 Cabins
$42,500
USD
Per Day
4 Days +
Flexible
44 Guests
22 Cabins
river Cruise
Private Charter
Pure Amazon
A state-of-the-art riverboat offering personalized and luxurious adventures in the Peruvian Amazon.
Regions:
Amazon, Peru
Destinations:
Peru Amazon
Cabins
/ Charter
$5,469
USD
Per Person
4 - 8 Days
3 Itineraries
22 Guests
12 Cabins
$23,750
USD
Per Day
Days +
Flexible
22 Guests
12 Cabins
Deal
20% OFF Early Booking Discounts on Zafiro, Perla, and Amatista
Honeymoon Cabin Upgrade onboard Zafiro Amazon Cruise
river Cruise
Private Charter
La Perla
Authentic Amazon cruising in a fun and comfortable vessel tailor made for adventure.
Regions:
Amazon, Peru
Destinations:
Iquitos, Peru Amazon
Cabins
/ Charter
$1,929
USD
Per Person
4 - 7 Days
3 Itineraries
28 Guests
14 Cabins
$15,323
USD
Per Day
4 Days +
Flexible
28 Guests
14 Cabins
Deal
20% OFF Early Booking Discounts on Zafiro, Perla, and Amatista
river Cruise
Private Charter
Amatista
A charming, authentic riverboat offering intimate, immersive Amazon exploration with modern comforts.
Regions:
Amazon, Peru
Destinations:
Iquitos, Peru Amazon
Cabins
/ Charter
$1,639
USD
Per Person
4 - 7 Days
3 Itineraries
29 Guests
14 Cabins
$10,900
USD
Per Day
4 Days +
Flexible
29 Guests
14 Cabins
Deal
Enjoy 1 Complimentary Night on 2026 Charters of 4+ Nights aboard the Kontiki Yatch
coastal Cruise
Private Charter
Kontiki Wayra
Contemporary wellness-themed yacht pioneering exploration of Costa Rica & Panama's Pacific coasts.
Regions:
Costa Rica, Panama
Destinations:
Del Caño Island, Drake Bay, Golfo Dulce, Jimenez Port, Los Sueños, Manuel Antonio National Park, Tortuga Island
Cabins
/ Charter
$4,179
USD
Per Person
5 - 8 Days
4 Itineraries
18 Guests
9 Cabins
$20,000
USD
Per Day
8 Days +
Flexible
18 Guests
9 Cabins
Deal
Up to 30% Off on Galapagos Cruises
Dedicated Solo Cabins
The "Willing to Share" Program
Flight Discounts On Galapagos Cruises
coastal Cruise
Private Charter
Galaxy Sirius
A stylish, sleek, and luxurious catamaran with balcony cabins sailing shorter Galapagos cruises.
Regions:
Galapagos, Ecuador
Destinations:
Bartolomé, Española, Floreana, Isabela, North Seymour, San Cristobal, Santa Cruz
Cabins
/ Charter
$5,699
USD
Per Person
5 - 6 Days
3 Itineraries
16 Guests
9 Cabins
$91,200
USD
Entire Vessel
5 Days +
Flexible
16 Guests
9 Cabins
Deal
2026 Last Minute Savings 30% or 40% off onboard the Anakonda & Manatee Cruises
Buy One, Get One Discounted on Select 2026 Sailings
river Cruise
Private Charter
Anakonda
Award-winning boutique vessel exploring Ecuador's biodiverse Oriente in luxurious style.
Regions:
Amazon, Ecuador
Destinations:
Ecuador Amazon, Coca
Cabins
/ Charter
$2,979
USD
Per Person
4 - 8 Days
3 Itineraries
36 Guests
18 Cabins
$26,135
USD
Per Day
4 Days +
Flexible
36 Guests
18 Cabins
Deal
Free Air to/from Galapagos aboard the Monique Catamaran!!
coastal Cruise
Private Charter
Monique
A cutting-edge catamaran offering an intimate and ultra-stable sanctuary for Galápagos exploration.
Regions:
Galapagos, Ecuador
Destinations:
Galapagos, Bartolomé, Española, Fernandina, Floreana, Isabela, North Seymour, San Cristobal, Santa Cruz
Cabins From
$4,169
USD
Per Person
4 - 8 Days
4 Itineraries
16 Guests
9 Cabins
$15,700
USD
Per Day
Days +
Flexible
16 Guests
9 Cabins
